States in the Northwest keep pressure on vaccine-derived polio

Kano, 9 September, 2021 – On 25 August 2021, African countries marked one-year anniversary of Polio certification. Programme managers, health workers and polio survivors in Nigeria also celebrated the wild polio- free status in the country.

The victory notwithstanding, the fight against other forms of the poliovirus is not over. Cases of vaccine-derived polio caused by low and infrequent immunization are still being recorded in Nigeria, with the northwest accounting for more than 55% of the total cases in the country highlighting the need for continued vigilance to nip a possible outbreak in the bud.

The Kano State Commissioner for Health, Dr Aminu Ibrahim Tsanyawa says, “The circulating vaccine derived polio Virus type -2 outbreak indicates the importance of continuing to receive Routine Immunization (RI) that is available in our health facilities, in order to reduce the risk of polio. That is why, expeditious action must be taken to strengthen our children’s immunity, to prevent further spread of the disease in our state and the country as a whole”.

Following the report in late 2020 of cases of vaccine-derived polio virus (cVDPV) disease in the northwestern states (Jigawa, Kano, Kaduna, Katsina, Kebbi, Sokoto and Zamfara), health authorities there are unrelenting in their actions to vaccinate all children under five years (10,637,566); the age at which the vaccine-derived polio disease is likely to set in.

“We continue to do this work because it is important for the children’s future,” says 26-year-old Amina Ibrahim, a vaccinator in Sokoto who works in communities despite the COVID-19 pandemic. “What we do is make sure we wash our hands, wear our face masks and maintain two-meters physical distance as we go from house to house.”

Addressing menace of cVDPV

First discovered in Madagascar in 2001, circulating vaccine-derived polio often occurs when a child who has been vaccinated with the oral polio vaccine (OPV) and who is in a poor sewage area passes stool or urine. The weakened live virus present in the urine or stool could find its way into the systems of other under-immunised kids through contaminated water or food and mutate, becoming infectious and causing life-long paralysis and in some cases, death.

Circulating vaccine-derived polio is rare but it poses risks to children everywhere because of its highly infectious nature. Nigeria has been experiencing outbreaks since 2018. The disease is fought in the same way wild polio is: with vaccines that provide the most important protection for children.

To halt the emergence of more cases of the disease, Northwest zone authorities are pushing massive statewide vaccination campaign. With a population of 53,187,831 (2021 projected), the zone is targeting about almost 11 million children during outbreak response vaccination exercises.

While the oral polio vaccine was used to protect against wild poliovirus in Nigeria, vaccine-derived polio disease is warded off with the novel oral polio vaccine (nOPV2). The World Health Organization (WHO) recommends regular immunization, at least twice for children, to reduce risks of infection. House to house team members administer two drops of the vaccine to produce a stronger immune response, according to the WHO.

Maintaining vigilance

Health authorities in all the seven states are also intensifying surveillance with the help of community informants to identify and isolate possible cases of vaccine-derived polio disease in the various local government areas.

Supported substantially by WHO, health officers regularly monitor the environment as well, examining stool and sewer samples in at-risk communities to monitor virus activity, a method that proved useful in finding and isolating wild poliovirus cases in the past years.

The surveillance and vaccination efforts are crucial for the northwest of mostly farmers and cattle herders. In the zone, the state’s geography makes it an easy target for infections. In the NWZ, four states share borders with Niger Republic which recorded cVDPV in 2020. The borders in the West African region are widely known to be porous and polioviruses are themselves highly infectious. In 2008, cases of wild polio spread from Nigeria to countries as far as Yemen.

Parents and caregivers mobilized for vaccination

The thoughts of life-time paralysis have made Sokoto parents especially eager to see their kids protected with vaccines. While years back parents saw many cases of children affected by polio growing up, the difference is clear now, with fewer children having to go through the pain of paralysis. Nigeria’s polio successes, hyped by traditional institutions, also boosted confidence in vaccines, a significant feat in a population that is often wary of medical services seen as foreign.

“In the North West Zone, traditional institutions have a renewed commitment to support WHO in tackling the upsurge of cVDP2 through improved community sensitization to achieve optimal routine immunization coverage across the zone”, says Dr Jalal Saleh, WHO Zonal Coordinator.

Ladidi Mohammed, a 16-year-old mother in Kazaure LGA Jigawa state says, “I allowed my child to be vaccinated because I believe my child will be protected from diseases of Polio, measles, Meningitis and other childhood diseases. Our traditional leader always sensitizes us on the importance of vaccination and I thank government for ensuring that our children are vaccinated and prevented from getting infected.”

But despite the vaccination push, health workers say they face hurdles in reaching some populations, leading to low vaccination coverage, especially with the impact of Covid 19 disease lockdown.

Residual challenges

Parts of the NWZ are insecure due to activities of bandits, armed groups, for one and another, rumours around vaccines, with one rumour saying they cause infertility in children. It is also challenging to reach nomadic cattle herding groups who make up a significant population in Nigeria’s north.

Crucially, because of inadequate education, many do not believe in the need to be vaccinated after polio has been declared eradicated and are shunning ongoing vaccinations against both wild and vaccine-derived polio.

These factors have resulted in Nigeria recording 201 outbreaks of vaccine-derived polio between 2018 and 2021 alone. Authorities declared a state of emergency on routine immunization in 2017, created state and local emergency routine immunization coordination centers and directed more state resources towards delivering vaccines.

“There has been a resurgence of vaccine-derived poliovirus over the years because there’s a significant proportion of under-immunized children,” says Dr Walter Kazadi Mulombo, WHO Nigeria Country Representative. “WHO will continue to support the country with experienced personnel in conducting effective immunization drives particularly in the outbreak areas”.

Despite the challenges, health workers continue to deliver vaccines and hop door to door and are helping parents understand the benefits of vaccines. Nomad trails are tracked with geo-information mapping systems so that vaccinators always know where families are. In communities with poor health infrastructure, state authorities and WHO are supplying drugs for minor ailments to build trust. And there is a productive collaboration with security agencies and local security groups that is helping health workers deliver vaccines safely to conflict-affected communities.

Source: World Health Organization. Africa

COVID-19 variants prolong Africa’s pandemic wave

Brazzaville – Weekly COVID-19 cases in Africa fell by more than 20%—the sharpest seven-day decline in two months – as the third wave pandemic tapers off. However, the rate of deceleration is slower than the previous waves owing to the impact of more transmissible variants.

The continent recorded more than 165 000 cases in the week ending on 5 September—23% lower than the week before, yet still higher than the weekly cases recorded at the peak of the first wave.

The more contagious Delta variant that partly fuelled the third wave has been dominant in several countries that experienced COVID-19 surge. In southern Africa, for instance, where more than 4000 COVID-19 genome sequencing data was produced in August, the Delta variant was detected in over 70% of samples from Botswana, Malawi and South Africa, and in over 90% from Zimbabwe.

“While COVID-19 cases have declined appreciably, the downward trend is frustratingly slow due to the lingering effects of the more infectious Delta variant,” said Dr Matshidiso Moeti, World Health Organization (WHO) Regional Director for Africa. “We are spearheading critical work and supporting countries in scaling up pathogen surveillance through genome sequencing to detect and respond effectively to COVID-19 variants.”

In collaboration with the South African National Bioinformatics Institute, WHO is at the forefront of the efforts to set up the Regional Centre of Excellence for Genomic Surveillance and Bioinformatics in Cape Town. The centre will support 14 countries before being expanded to serve more countries. Last year, WHO and partners established a COVID-19 sequencing laboratory network in Africa which has to date produced nearly 40 000 sequencing data.

“The continent lags far behind the rest of the world when it comes to sequencing, with only 1% of over 3 million COVID-19 sequences conducted worldwide occurring in Africa,” said Dr Moeti. “The third wave has shown us how variants can hijack the efforts to tame the pandemic. Countries must step up surveillance because without genomic information, variants can spread undetected. You can’t fix what you don’t measure.”

WHO has also recently provided financial support to countries including Eswatini, Sao Tome and Principe and Senegal to reinforce genomic surveillance. To date, the dominant Delta variant has been detected in 31 African countries, while the Alpha and Beta variants have respectively been identified in 44 and 39 countries.

The C.1.2 variant initially identified in South Africa has so far been detected in 130 cases in 10 countries globally, including five in Africa. Although the variant has exhibited concerning mutations, there is no evidence that it is more transmissible or may affect vaccine efficacy, but more research is needed.

As Africa’s third COVID-19 pandemic wave eases off, vaccine shipments to the continent continue to grow, with around 5.5 million doses received through COVAX in the first week of September. However, only around 3% of the continent’s population is fully vaccinated.

“To ultimately tip the scales against this pandemic, our best efforts to reduce transmission through public health measures must be met by a significant step-up in vaccine supplies and vaccinations,” Dr Moeti said.

Dr Moeti spoke during a virtual press conference today facilitated by APO Group. She was joined by Professor Alan Christoffels, Director of the South African National Bioinformatics Institute, and Dr Christian Happi, Professor of Molecular Biology and Genomics and Director at the African Centre of Excellence for Genomics of Infectious Diseases at Redeemer’s University in Nigeria.

Also on hand to respond to questions were Dr Nicksy Gumede-Moeletsi, Regional Virologist, WHO Regional Office for Africa, Dr Richard Mihigo, Coordinator, Immunization and Vaccines Development Programme, WHO Regional Office for Africa, and Dr Thierno Balde, Regional COVID-19 Deputy Incident Manager, WHO Regional Office for Africa.

Source: World Health Organization. Africa

Liberia receives additional 108,000 Doses of COVID-19 J&J Vaccine through World Bank

On 3rd September 2021, Liberia received 108,000 Johnson and Johnson COVID-19 vaccine doses shipped via the African Union (AU), African Vaccine Acquisition Trust (AVAT) initiative, a partnership with UNICEF with funding from the World Bank.

These deliveries are part of the historic COVID-19 vaccine advance procurement agreement signed by AVAT and World Bank for the purchase of 108,000 thousand doses of the Johnson & Johnson single-shot COVID-19 vaccine. On June 30, 2021, the World Bank approved USD 8 million dollars additional financing to support both the acquisition and equitable deliverable deployment of vaccines.

AVAT was established by the African COVID-19 Vaccine Acquisition Task Team, set up in November 2020 under the African Union chairmanship of HE President Cyril Ramaphosa, President of the Republic of South Africa, as part of the African Union’s COVID-19 Vaccine Development and Access Strategy, and its goal of vaccinating at least 60 per cent of the African population with safe and efficacious vaccines against COVID-19.

Liberia will receive a total of 386,452 doses of Johnson and Johnson vaccine through AVAT mechanism. This will contribute to the WHO target of vaccinating 10% of the population by end of September and 40% by December 2021.

Speaking during the handing over of the vaccines at the Roberts International Airport in Margibi County, The Honorable Dr. Wilhelmina Jallah, Health Minister of the Republic of Liberia expressed gratitude for another batch of supplies of vaccines to Liberia. “Tonight is another milestone for all of us and to all who are still sitting on the fence and deciding, the vaccines are getting better and better” Min. Jallah said.

“We need to prepare and enhance immunity by vaccination against Covid-19 as we continue to use other preventive measures. We are making sure we go to where we should be by the end of September, December and next year, as nobody knows when COVID-19 will end” Min Jallah.

On behalf of the UN family, Mr. Niels Scott, United Nations Resident Coordinator in Liberia said the ongoing COVID-19 vaccination in Liberia is an evidence to the change in the paradigm of COVID-19 vaccines being administered to only people in wealthy countries. “So far, 80% of all vaccines globally that has been administered have gone to the wealthier countries, the high income, upper middle income countries. We are changing this” He added.

The Acting Country Manager of World Bank, Mr. Mark Mulbah congratulated the Liberian government and its partners, the African Vaccine Acquisition Trust (AVAT) and the African Union for the delivery of these 108,000 Johnson and Johnson COVID-19 vaccine doses.

Among others to receive the COVID-19 vaccines at the Roberts International Airport were officials from the Government of Liberia, World Bank, UN Agencies including WHO and UNICEF and several health development partners.

Source: World Health Organization. Africa

Sierra Leone receives 151,200 J&J COVID-19 vaccines donated by US Govt. via COVAX Facility

The United States Government has donated 151,200 doses of the Johnson & Johnson COVID-19 vaccine to Sierra Leone to help accelerate the current COVID-19 vaccination drive in the country.

The United States has made this donation through the COVAX facility, a global coalition co-led by the WHO, Gavi, the Global Vaccines Alliance and the Coalition for Epidemic Preparedness Innovations (CEPI), working in partnership with developed and developing country vaccine manufacturers, UNICEF, the World Bank, and others on the equitable distribution of COVID-19 vaccines to countries regardless of their income.

This brings to 838 000 doses of COVID-19 vaccines, which have been received by Sierra Leone under the COVAX facility since the country rolled out COVID-19 vaccinations in March this year.

Dr Austin Demby, Minister of Health and Sanitation, said “The Government appreciate the substantial support of donated vaccines from the Government of the United States. This will contribute immensely towards accomplishing vaccine equity in Sierra Leone and the Government will make certain that more people will be vaccinated in the shortest possible time.”

The donation of Johnson & Johnson vaccines to Sierra Leone is part of the U.S. government’s global vaccine-sharing strategy, which aims to support countries most affected by the pandemic and is part of the broader support by the U.S. Government to help prevent further spread of COVID-19.

“We are proud to support COVAX’s commitment to rapidly and equitably save lives and bring an end to the COVID-19 pandemic. The delivery of 151,200 Johnson & Johnson doses to Sierra Leone is an important step toward that goal,” said USA Ambassador to Sierra Leone, H.E. David Reimer.

The COVAX Facility has been instrumental in supporting low and middle-income countries to access COVID-19 vaccines and supporting governments with the development of national vaccination plans, cold chain infrastructure and related operational equipment, logistical materials, and medical supplies to facilitate smooth implementation of vaccination activities.

Through this facility, Sierra Leone has so far received the AstraZeneca-Oxford vaccines, which arrived in March and August. These vaccines, together with the consignment of vaccines received through other arrangement by the Government of Sierra Leone, have helped reach more than 264,256 adults with the first dose of COVID-19 vaccines, while more than 64,749 have since received their second doses as of the first week of September 2021. This continued flow of vaccines into the country is welcome as it helps to sustain the current intensified vaccination drive, which has also opened vaccination to all adults above the age of 18 years.

“We are delighted to see U.S.-donated J&J doses arriving in Sierra Leone. This shipment will provide protection from COVID-19 for over 150,000 people, helping to stem the tide. COVAX is committed to ending the acute phase of the pandemic, and the strong support of the United States Government is crucial in getting us there.” Patience Musanhu, Senior Country Manager.

The Johnson & Johnson single shot vaccines have been approved by the WHO as effective in protecting people against COVID-19. This arrival of the vaccines to Sierra Leone is timely as demand for vaccine is steadily increasing in Sierra Leone

With less than 2 percent of eligible adults currently being fully vaccinated in Sierra Leone, these additional vaccines will serve to fill in the current gaps. Within the coming weeks, the United States Government, through COVAX dose-sharing mechanism, intends to deliver another batch of COVID-19 vaccines to the country.

“Over the past one month, we have seen remarkable improvement and momentum at all levels of strategic partnership and cooperation in enhancing vaccine equity, national strategies in vaccine administration, and increased interest in vaccine uptake by the eligible members of the public. This is an important moment to strengthen our collaboration and support to the government to reach the vaccination targets and goals and protect the population against this pandemic”, said Dr Steven V. Shongwe, WHO Representative in Sierra Leone.

UNICEF is leading the procurement and delivery of the various COVID-19 vaccines reaching Sierra Leone through the COVAX facility. Further to this logistics support, UNICEF continues to support the Government of Sierra Leone’s vaccine rollout exercise through planning, cold chain management, demand generation, and capacity building of health workers.

“The unprecedented COVID-19 crisis can only be tackled when the world acts together as one,” said UNICEF Representative, (acting in charge) Ms. Liv Elin Indreiten. “UNICEF is therefore proud to be part of this global partnership to help people across Sierra Leone receive the vaccines and remain protected from serious illness or death due to COVID-19.”

COVAX has built a diverse portfolio of vaccines suitable for a range of settings and populations, and is on track to meet its goal of delivering at least 2 billion doses of vaccine to participating countries around the globe in 2021, including at least 1.3 billion donor-funded doses to the 92 lower-income COVAX Facility participants supported by the Gavi COVAX AMC. The United States is the largest contributor to COVAX.

Officials from the government of Sierra Leone, U.S. Embassy, United Nations Agencies including the World Health Organization and UNICEF and several health developments partners, attended the ceremonial handover of the vaccines to the Ministry of Health and Sanitation.

Source: World Health Organization. Africa

KOICA, MOH, NPHIL and stakeholders conduct health service resilient (HSR) project Midterm Review (MTR) in Liberia

Midway the Korea International Cooperation Agency (KOICA)-funded project on “Making Health Systems Resilient to Public Health Emergencies with Quality Services and Emergency Preparedness and Response,” KOICA, WHO, Ministry of Health (MOH), and National Public Health Institute of Liberia (NPHIL) along with stakeholders have undertaken a midterm review (MTR) of the project implementation from September 2-3, 2021 at the Corina Hotel in Monrovia, Liberia. The MTR analyzed key lessons learned and best practices through the project implementation and assessed emerging challenges as well as collated recommendations from key stakeholders to streamline the project, improve results and ultimately ensure the achievement of the project outcomes and further inform the next phase of the project implementation in Liberia (2021-2023).

Held under strict adherence to COVID-19 protocol, the both virtual and in-person meeting brought together fifty (50) key stakeholders from eleven (11) healthcare facilities in the three (03) project counties, national and international levels (including KOICA-Nigeria Office, WHO-Headquarters) and other partner organizations.

Speaking during the opening of the MTR Workshop, Hon. A. Vaifee Tulay, Deputy Health Minister for Policy Planning, Monitoring and Evaluation and Research on behalf of the Honorable Minister of Health for Liberia, Dr. Wilhelmina Jallah, acknowledged the efforts of partners, especially WHO and the Korean Government for their support to Liberia health sector in enhancing quality healthcare service delivery during outbreaks and non-outbreak situations. “It is midway into the project implementation and new realities, like COVID-19 outbreak and re-emergence of EVD and Marburg threats have emerged. This is the reason why we need to revisit the dashboard to identify what went well, what did not go well and why, and how we can redesign the project or prioritize activities to respond to the current needs of the Country,” Minister Tulay said.

Dr. Zabulon Yoti, WHO Acting Country Representative applauded the collaboration and commitment of the MOH, NPHIL, relevant institutions and partners towards building a resilient health system in Liberia. “The importance of resilient health systems to tackle and withstand public health emergencies like COVID-19, while providing quality routine health services, cannot be overstated” Dr. Yoti said. He reiterated WHO’s commitment for continued partnership with the MOH, donors, KOICA, and partners in this endeavor.

For his part, Dr. Sohel Saikat, the overall KOICA Project Lead expressed satisfaction that the collaboration with KOICA has brought WHO’s expertise in health systems, global health security agenda, as well as disease/life course under one platform. He said for too long we have seen emergencies and health systems working parallel or in silos, isolated from one another and now responding to COVID-19, there is more like this and other challenges with us and ahead. “Strong and resilient health systems – equipped with and prepared for emergency – are our best line of defense. This reduces the risks of small events turning into emergencies,” Dr. Sohel highlighted. He then applauded the Korean Government for the partnership that KOICA and WHO continue to demonstrate in addressing the many challenges confronting the health systems of Liberia, Ethiopia and other countries alike.

Since its inception in Liberia (April 2019), the KOICA-funded HRS project continues to adopt a collaborative, participatory and multisectoral approaches to ensure close engagement with the project teams, government counterparts, donor, beneficiaries, and other key stakeholders in achieving several milestones in line with national priorities and the overall project objectives.

To this end, the review team believes that if the recommendations from the gaps identified: i) knowledge sharing and benchmarking of best practices ii) monitoring and tracking of health service quality and resilience indicators iii) roll out the training package for Health Service quality and resilience iv) Launching and application of the Health System Simulation (SimEx) package v) Institutionalization of health service quality and resilience into pre- and in-service training programs and vii) adaptation and roll out of technical guidance for health service resilience e.g. Health Service Continuity Planning are implemented, it is likely that the milestones of the KOICA funded project will be achieved by 2023. The stakeholders also called on WHO and KOICA to roll out the project in other health facilities, considering its impacts; and pledged to take measures to ensure sustainability and continuity of the interventions.

Both emerging and reemerging health emergencies have underscored the importance of quality health services with emergency preparedness in health system. This was observed in different public health events such as the 2014-15 Ebola virus disease (EVD) outbreak in Liberia and the COVID-19 pandemic. As part of Liberia’s recovery process after the 2014-15 EVD outbreak to ensure health system functionality to maintain routine and emergency related healthcare services and response, key integrated approaches were identified. However, the operationalizing those integrated approaches in county level institutions and services remained a challenge.

The KOICA funded five-year project (2018 – 2023) on making health services resilient for public health emergencies was approved for Liberia along with Ethiopia, with the aim to build and strengthen resilient health care services to improve emergency preparedness while providing quality routine health services. Nineteen (19) healthcare facilities (public and private) from three (03) counties were selected to pilot the HSR project in Liberia.

Source: World Health Organization. Africa

Democratic Republic of the Congo declares meningitis outbreak in north-eastern province

Kinshasa – The Democratic Republic of the Congo has declared an outbreak of meningitis in the north-eastern Tshopo Province where 261 suspected cases and 129 deaths—a high case fatality ratio of 50%—have been reported.

Confirmatory tests carried out by the Institut Pasteur in Paris detected Neisseria meningitidis – one of the most frequent types of bacterial meningitis with the potential to cause large epidemics.

The health authorities have deployed an initial emergency team, and with the support of the World Health Organization (WHO), efforts are underway to quickly ramp up the response. A crisis response committee has been set up in Banalia, the community affected by the outbreak, as well as in Kisangani, the capital of Tshopo, to accelerate the outbreak control efforts. WHO has provided medical supplies in Banalia and plans to deploy more experts and resources.

“Meningitis is a serious infection and a major public health challenge. We are moving fast, delivering medicines and deploying experts to support the government’s efforts to bring the outbreak under control in the shortest possible time,” said Dr Matshidiso Moeti, WHO Regional Director for Africa.

More than 100 patients are already receiving treatment at home and in health centres in Banalia. Meningitis is transmitted among people through droplets of respiratory or throat secretions from infected people. Close and prolonged contact or living in close quarters with an infected person facilitates the spread of the disease. Although people of all ages can catch the disease, it mainly affects babies, children and young people.

“We are scaling up control measures within the community and rapidly investigating suspected cases in surrounding localities to treat patients and curb potentially widespread infections,” said Dr Amédée Prosper Djiguimdé, WHO Representative in the Democratic Republic of the Congo.

More than 1.6 million people aged between 1 and 29 years were vaccinated in a massive campaign in 2016 in Tshopo, which lies in the African meningitis belt that runs across the continent from Senegal to Ethiopia and comprises 26 countries. The African meningitis belt is the most vulnerable globally to recurrent outbreaks.

Meningitis outbreaks have occurred in several provinces of the Democratic Republic of Congo in the past. In 2009, an outbreak in Kisangani infected 214 people and caused 15 deaths—a case fatality ratio of 8%.

Meningitis is potentially fatal and is a medical emergency. Admission for treatment is necessary and appropriate antibiotic treatment must be started as soon as possible. Over the years, major improvements have been made on vaccines, which are specific to the type of meningitis.

In November 2020, the World Health Assembly—the global health policy-setting body—approved a roadmap for a meningitis-free world by 2030, with three key objectives: elimination of bacterial meningitis, reduction of vaccine-preventable bacterial meningitis by 50% and deaths by 70%, as well as reduction of disability and improvement of quality of life after meningitis.

Source: World Health Organization. Africa

Eswatini holds an inaugural virtual national health research conference

The Kingdom of Eswatini successfully hosted an inaugural virtual national health research conference from 26 to 27 August 2021. The conference was held under the theme “COVID-19, an emergency and evolving Global Public Health threat; the Role of Research”. It was organised by the Ministry of Health (MOH) in collaboration with Ministry of Information, Communication and Technology (ICT) and supported by the International Center for AIDS Care and Treatment Programs (ICAP), The U.S. President’s Emergency Plan for AIDS Relief (PEPFAR) and the the World Health Organization (WHO).

The conference was opened by His Excellency the right Honourable Prime Minister of the Kingdom of Eswatini Mr Cleopas Sipho Dlamini who was represented by the Minister of Agriculture Honourable Jabulani Mabuza. Also present at the official opening was Minister of Health Senator Lizzie Nkosi, US Ambassador Her Excellency Jeanne Maloney, the WHO Country Representative Dr Cornelia Atsyor, Principal Secretaries in the Ministry of Health and Ministry of Information, Communication and Technology and other senior government officials.

The conference brought together international and local scientists, health professionals, policy makers, researchers, the private sector, academia and development partners. The aim of the conference was to ponder and intensify debate around the evidence underpinning the COVID-19 pandemic. The world is now a year and half into the COVID-19 pandemic; hence it is opportune time to review and share the numerous lessons learnt and look at the challenges that still exist.

Speakers and presenters highlighted how research and innovation has helped scientist to deliver rapid diagnostics for use in community settings, identify optimal protective equipment (PPE) to protect health care workers and the public, evidence-based infection prevention and control (IPC) measures such as mask-wearing and social distancing in health care and community settings as well as major clinical trials for the evaluation of candidate therapeutics, identifying a handful of which have had positive results on cutting deaths.

It was also emphasised that research and the evidence that research yields are critical elements for improving national health security and health equity, as well as economic development. Research and Development has delivered safe and efficacious COVID-19 vaccines at an unprecedented speed.

In his speech the Prime Minister mentioned that the Government of the Kingdom of Eswatini has prioritised research and is one of the strategic directions in the post COVID-19 Economic Recovery Plan and the National Development Plan. The Prime Minister also emphasised that the world is constantly evolving hence the need to provide information about global trends and most importantly, local factors is imperative. This allows for interventions, approaches and strategies that are responsive to the current challenges.

“The past two years have cemented and emphasized the importance of research, particularly in the health sector. Events such as this conference propel collaborations and potential linkages; allowing for knowledge dissemination and knowledge fluidity,” he said.

The Prime Minister also noted that the COVID-19 has given us the opportunity to fast track policy reforms that will enable Science, Technology and Innovation to be prioritized and used to attain sustainability across all sectors. He noted that the world is now moving towards a knowledge-based economy and research is a crucial component to effectively champion development. He emphasized that as the world ventures into new territory, it’s time to act and think anew; and most importantly rise to the occasion.

“Worth mentioning is the role of research in mitigating the impact of the virus and the vaccines developed to control the virus. The role and importance of research can, therefore, not be understated. Research provides the solutions needed to combat the challenges faced by health care systems worldwide, he said.

The WHO Country Representative Dr Atsyor said that high-quality research is essential for “the attainment by all peoples of the highest possible level of health. She noted that there have been lessons at every stage of the response to the pandemic. She added that research, evidence, and information are the foundation for sound health policies.

Furthermore, ICAP Wafaa El Sadr, applauded the government of Eswatini recognizing the importance capacity building on human and health research through in service and preservice training. The Ministry of Health strongly supported the Health Research Training Program (HRTP) where over a period of 5 years, 40 fellows were enrolled into a one-year research mentorship program that provided practical research skills.

Different researchers made presentations during the two-day conference, sharing lessons learnt, best practices and challenges observed during the response to the pandemic. During the closing of the conference, Minister of Health who was represented by the Principal Secretary in the Ministry of Health, Dr Simon Zwane expressed appreciation to the scholars and scientists who shared their knowledge with guests. She made emphasis that the vast knowledge shared at the conference will go a long way in shaping policy and helping the country to respond better to the COVID-19 pandemic.

Source: World Health Organization. Africa

COVID-19: ANGOLA REPORTS 214 NEW INFECTIONS, 10 DEATHS

Luanda – Angola reported this Saturday 214 new cases, 10 deaths and the recoveries of 22 patients in the last 24 hours.

According to the daily bulletin, there are 121 new cases in Luanda, 29 in Huíla, 21 in Cuando Cubango, 15 in Huambo, 9 in Namibe, 7 in Bié, 3 in Lunda Sul, 3 in Zaire, 2 in Moxico, 1 in Bengo, 1 in Benguela, 1 in Cabinda and 1 in Cuanza Sul.

With ages ranging from 11 days to 103 years, the group consists of 109 males and 105 females.

Of the deaths, 4 were reported in Cuando Cubango, 4 in Huíla, 1 in Bié and 1 in Luanda.

Among those recovered, 13 lives in Huíla, 5 in Huambo, 3 in Cuando Cubango and 1 in Moxico.

In the last 24 hours, laboratories have processed 2008 blood samples.

In the treatment centers there are 199 people hospitalized, while 172 citizens are in institutional quarantine and 1,164 contacts of positive cases are under medical surveillance.

Angola has a total of 48,475 positive cases, with 1,258 deaths, 43,817 recoveries and 3,400 active. Of the active, 12 are critical, 29 serious, 112 moderate, 46 mild and 3201 asymptomatic.

Source: Angola Press News Agency

COVID-19: OVER TWO MILLION PEOPLE VACCINATED IN ANGOLA

Caxito – The Secretary of State for Hospital Areas, Leonardo Inocêncio, said Saturday in Bengo that 2,119,729 Angolans had been vaccinated against Covid-19 in Angola.

The number of doses administered accounted for 5.7 percent of the target public (health professionals, defence and security forces, teachers, social workers and patients with comorbidities) in the vaccination campaign.

He said that the national vaccination plan provided for the vaccination of over 15 million people in the country.

Leonardo Inocêncio said this at the launch of a national campaign to sensitise the public so that they adhere to the Covid-19 vaccination posts, promoted by JMPLA in Panguila market (Bengo).

In Bengo province, he said, more than 20,000 doses of vaccine are available, appealing for the adhesion to the campaign as the vaccine is safe and effective.

Source: Angola Press News Agency

Eight in 10 African countries to miss crucial COVID-19 vaccination goal

Brazzaville – Africa is set to miss the urgent global goal of vaccinating the most vulnerable 10% of every country’s population against COVID-19 by the end of September. Forty-two of Africa’s 54 nations—nearly 80%—are set to miss the target if the current pace of vaccine deliveries and vaccinations hold, new data from the World Health Organization (WHO) shows.

Nine African countries, including South Africa, Morocco and Tunisia, have already reached the global target set in May by the World Health Assembly, the world’s highest health policy-setting body. At the current pace, three more African countries are set to meet the target. Two more could meet it if they speed up vaccinations.

“With less than a month to go, this looming goal must concentrate minds in Africa and globally. Vaccine hoarding has held Africa back and we urgently need more vaccines, but as more doses arrive, African countries must zero in and drive forward precise plans to rapidly vaccinate the millions of people that still face a grave threat from COVID-19,” said Dr Matshidiso Moeti, WHO Regional Director for Africa.

Almost 21 million COVID-19 vaccines arrived in Africa via the COVAX Facility in August, an amount equal to the previous four months combined. With more vaccines expected from COVAX and the African Union by the end of September, we could see enough doses delivered to meet the 10% target.

While many African countries have sped up COVID-19 vaccinations as vaccine shipments ramped up in August, 26 countries have used less than half of their COVID-19 vaccines.

Over 143 million doses have been received in Africa in total and 39 million people—around just 3% of Africa’s population—are fully vaccinated. In comparison, 52% of people are fully vaccinated in the United States of America and 57% in the European Union.

“The inequity is deeply disturbing. Just 2% of the over five billion doses given globally have been administered in Africa. Yet recent rises in vaccine shipments and commitments shows that a fairer, more just global distribution of vaccines looks possible,” said Dr Moeti.

Countries must continue to address operational gaps and continually improve, adapt and refine their COVID-19 vaccination campaigns. Of the 30 countries that have submitted data to WHO on operational readiness, one in two have not conducted intra-action reviews, which are key to assessing and fine-tuning progress. One in three countries have not updated their National Vaccine Deployment Plans, which instruct all COVID-19 vaccination actions in each country.

WHO is providing tailored policy advice and technical guidance and support to African countries to help enhance their logistics, planning and monitoring capacities. WHO is also working to share valuable lessons and experiences between countries.

COVID-19 cases are declining slightly in Africa but remain stubbornly high. A rising number of new cases in Central, East and West Africa pushed case numbers up to nearly 215 000 in the week ending on 29 August. Twenty-five countries—over 45% of African countries—are reporting high or fast-rising case numbers. Over 5500 deaths were reported in the week ending on 29 August.

“ Although Africa’s third wave peaked in July, the decline in new cases is at a glacial pace — far slower than in previous waves. The pandemic is still raging in Africa and we must not let our guard down. Every hour 26 Africans die of COVID-19.”

The highly transmissible Delta variant has been found in 31 African countries. The Alpha variant has been detected in 44 countries and the Beta variant in 39.

The C.1.2 variant has been identified in 114 cases in South Africa. Single cases have been found in four other African countries, and very low case numbers have been reported internationally. While first reported to WHO in July, the prevalence of this new variant remains very low. To be identified as a variant of concern there must be evidence of an impact on transmissibility, severity or immunity. This is not the case for the C.1.2 variant, yet more data is required.

“We are closely monitoring the spread and evolution of all reported variants of COVID-19, including C.1.2. Mask wearing, physical distancing and regular hand washing will help keep you safe from all variants,” said Dr Moeti.

Dr Moeti spoke during a virtual press conference today facilitated by APO Group. She was joined by Dr Nicholas Crisp, Deputy Director General, National Health Insurance, Department of Health, South Africa, and Dr Assan Abdoul Nasser, Director of Immunizations, Ministry of Public Health, Population and Social Affairs, Niger.

Also on hand to respond to questions were Dr Richard Mihigo, Coordinator, Immunization and Vaccines Development Programme, WHO Regional Office for Africa, and Dr Thierno Balde, Regional COVID-19 Deputy Incident Manager, WHO Regional Office for Africa.

Source: World Health Organization. Africa